I was reading the rulebook for 'Planet Mercenary', the RPG for Howard Tayler's 'Schlock Mercenary' universe this afternoon and I was absolutely delighted to see the game master's section has a section on making your games accessible, covering everything from wheelchair access to players with social anxiety. It's even written within the game's metanarrative* that it's a game for actual inhabitants of the Schlock Mercenary universe. There's a couple of slight mis-steps where it's arguably patronizing, and a faux pas in the segue to handling problem players in the next segment, but this is generally really well thought out - for instance, using a differently sized rather than differently coloured die if one of a set needs to be distinct and a player has a visual impairment that would stop them seeing that, and watching player body language for signs players are being triggered or otherwise driven out of the game. And of course the major step forward is that it's there at all.
* Also within the metanarrative, a short story told in the form of editorial comments - wow!